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KMID : 1013220060040010065
Jouranl of the Korean Society of Clinical Toxicology
2006 Volume.4 No. 1 p.65 ~ p.68
Two Cases of Contact Urticaria Syndrome from Cefotiam in Nurses
Jang Pyeong-Moon

Kim Ho-Jung
Lee Jung-Won
Kim Yong-Seung
Cho Young-Shin
Yu Ki-Won
Lim Hoon
Abstract
Contact urticaria describes a wheal and falre response elicitied within 30-60 minutes after cutaneous exposure to certain agents. Contact urticaria encompasses a number of different clinical manifestations and the symptoms which can vary from the mildest forms of burning, stinging and itching sensation to life-threatening anaphylaxis referred to as contact urticaria syndrome. Cefotiam is one of the most popular second generation cephem antibiotic used in korea. Since 1975, contact urticaria due to cephalosporins has been reported, and also, in japan, this reported from about last 15 years. Recently we experienced three nurses working at the general wards with showing contact urticaria and anaphylaxis after occupational exposure to cefotiam antibiotics.
KEYWORD
Cefotiam, Contact urticaria syndrome
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